Sylvie Assadourian Selected Research

SAR125844

10/2017

Phase I dose-escalation study of the c-Met tyrosine kinase inhibitor SAR125844 in Asian patients with advanced solid tumors, including patients with MET-amplified gastric cancer.

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Sylvie Assadourian Research Topics

Disease

7	Neoplasms (Cancer) 10/2017 - 02/2005
3	Proteinuria 01/2016 - 03/2012
3	Diarrhea 02/2007 - 02/2005
2	Disease Progression 01/2016 - 03/2012
2	Hypertension (High Blood Pressure) 01/2016 - 03/2012
2	Febrile Neutropenia 01/2016 - 01/2013
2	Stomatitis 01/2016 - 01/2013
2	Dysphonia (Spastic Dysphonia) 01/2016 - 03/2012
2	Neutropenia 01/2016 - 02/2007
2	Epistaxis (Nosebleed) 01/2016 - 03/2012
2	Abdominal Pain (Pain, Abdominal) 01/2013 - 02/2007
2	Nausea 02/2007 - 02/2005
1	Multiple Myeloma 01/2021
1	Stomach Neoplasms (Stomach Cancer) 10/2017
1	Lymphopenia (Lymphocytopenia) 01/2016
1	Pancreatic Neoplasms (Pancreatic Cancer) 08/2013
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2013
1	Thrombotic Microangiopathies 01/2013
1	Breast Neoplasms (Breast Cancer) 03/2012
1	Neuroblastoma 11/2008
1	Vomiting 02/2007
1	Rhabdomyosarcoma 02/2007
1	Anemia 02/2007
1	Thrombocytopenia (Thrombopenia) 02/2007
1	Adenocarcinoma 08/2005
1	Anorexia 02/2005
1	Colitis 02/2005

Drug/Important Bio-Agent (IBA)

4	afliberceptIBA 01/2016 - 03/2012
4	Irinotecan (Camptosar)FDA LinkGeneric 11/2008 - 02/2005
3	Docetaxel (Taxotere)FDA Link 01/2016 - 08/2005
2	Fluorouracil (Carac)FDA LinkGeneric 01/2016 - 08/2005
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 03/2012
2	Cisplatin (Platino)FDA LinkGeneric 01/2016 - 08/2005
2	AntiemeticsIBA 02/2007 - 02/2005
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021
1	pomalidomideIBA 01/2021
1	isatuximabIBA 01/2021
1	SAR125844IBA 10/2017
1	Tyrosine Kinase InhibitorsIBA 10/2017
1	Proteins (Proteins, Gene)FDA Link 01/2016
1	Ciprofloxacin (Cipro)FDA LinkGeneric 01/2016
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2016
1	Gemcitabine FDA Link 08/2013
1	Loperamide (Imodium)FDA LinkGeneric 02/2007
1	Cholinergic Agents (Cholinergics)IBA 02/2007
1	Atropine FDA LinkGeneric 02/2007
1	Capecitabine (Xeloda)FDA Link 02/2005

Therapy/Procedure

3	Drug Therapy (Chemotherapy) 01/2013 - 02/2007
1	Combination Drug Therapy (Combination Chemotherapy) 08/2005